UC-II® undenatured type II collagen
Lonza Capsules and Health Ingredients (United States)
Help pets keep up with their owners with UC-II® undenatured type II collagen.
Lonza’s UC-II® undenatured type II collagen is the next generation of joint health support for pets, providing brands with a science-backed solution for healthy and osteoarthritic companion animals.
Backed by a comprehensive body of evidence-based research—spanning more than two decades and multiple companion animal studies—UC-II® undenatured type II collagen has been shown to help maintain joint comfort, support a healthy inflammatory response, and help preserve joints in dogs.1,2 Its unique mechanism of action triggers the immune system to help support the body’s natural cartilage repair process and promote the building of cartilage.3
With one small daily dose of 40 mg,4,5 it is a convenient and formulation-friendly solution that can be easily integrated into numerous applications6—such as treats or chews—without compromising on effectiveness.
Lonza Capsules and Health Ingredients
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1 Varney, et al (2022). Impact of supplemented undenatured type II collagen on pain and mobility in healthy Labrador Retrievers during an exercise regimen. Transl Anim Sci, 6, 1-7
2 Varney et al. (2021). Undenatured type II collagen mitigates inflammation and cartilage degeneration in healthy dogs during an exercise regimen. Transl Anim Sci, 5(2).
3 Bagi et al. (2017). Oral administration of undenatured native chicken type II collagen (UC-II) diminished deterioration of articular cartilage in a rat model of osteoarthritis (OA). Osteoarthritis Cartilage, 25(12), 2080-2090.
4Gupta, R.C., et al. (2012), Comparative therapeutic efficacy and safety of type-II collagen (uc-II), glucosamine and chondroitin in arthritic dogs: pain evaluation by ground force plate. J Anim Physiol Nutr, 96: 770-777
5D’Altilio et al. (2007). Therapeutic efficacy and safety of undenatured type II collagen singly or in combination with glucosamine and chondroitin in arthritic dogs. Toxicol Mech Methods, 17, 189-196.
6Juturu, et al. (2021). Recovery of undenatured type II collagen from different prototypes of food and beverages using enzyme-linked immunosorbent assay (ELISA) [abstract]. Curr Dev Nutr, 5(2), 327.